Mushrooms to treat depression

[Wakinyan]

https://www.nature.com/articles/s41598-017-13282-7


"Psilocybin with psychological support is showing promise as a treatment model in psychiatry but its therapeutic mechanisms are poorly understood. Here, cerebral blood flow (CBF) and blood oxygen-level dependent (BOLD) resting-state functional connectivity (RSFC) were measured with functional magnetic resonance imaging (fMRI) before and after treatment with psilocybin (serotonin agonist) for treatment-resistant depression (TRD). Quality pre and post treatment fMRI data were collected from 16 of 19 patients. Decreased depressive symptoms were observed in all 19 patients at 1-week post-treatment and 47% met criteria for response at 5 weeks. Whole-brain analyses revealed post-treatment decreases in CBF in the temporal cortex, including the amygdala. Decreased amygdala CBF correlated with reduced depressive symptoms."

[Wakinyan]

The big take away from the above article seems to be that mushrooms taken every 1 to 5 weeks can help stave off depression in even treatment resistant depression.

[judih]

sounds like a fine plan.
(you can't control the waves, but you can learn to surf - jon kabat-zinn)