possible cure for cancer.. scientist, get on it ;)

[Arhuline]

Colhchicum autmnale grows from august to october on medows and forests with higher moisture, specially on +/- basicial or acid humus floor, more often on higher altutudes.

flos is coloured violet - red that procedes in some kind of petilus that is almost in the same colour as the flos and without leeves that grow next spring...
 nucel is under the surface in corrolla-tube...
here's a picture, dont mind the text 'cause it's in Hungarian  :shock:
http://images.google.com/imgres?imgurl= ... D%26sa%3DN

ok, here comes the interesting part:
the plant contains alkaloid Colchicine
this alkaloid stops cell division and the build up of amyloid and is used in homeopatics.

I was really brainstorming yesterday with a mug of coffie and some domestic XY sativa :roll:  and I whish that my conclusion is right. Cancer spreads - Colchicine stops...
seems logical to me.. but I guess I'll have to get some Brain pills first...


geee, I hope I'll pass my botanics tommorow

[Arhuline]

call me crazy...... :mrgreen:

[Finbar]

call me crazy...... :mrgreen:

Ok, you are crazy. Hehe.

Better be careful with thiz one, "All parts of the plant are very poisonous...." PDR for Herbal Medicines.

Sure, it iz antichemotaxis, but apparently some other property makez it poisonous. As colchicine iz used to treat gout.

In botany it iz used to increase the ploidy in plants...hence new mutationz. Make tha wrong mutation and cancer seemz more probable.

Some catz were trying to make a darker colored flower. They found the gene for that color flower and inserted an extra copy of the gene - hoping ta get tha darker flowerz. All the F2 flowerz were white. Turnz out, there iz something called RNAi - interference RNA. The RNAi attacked all genez that had tha extra copy for tha darker flowerz. Hence, all white flowerz. Tha guy will win the Noble for...fooking around with flowerz. RNAi also will cure many diseasez when we learn to harnass it - cancerz, alzheimer'z, maybe even AIDS.

//http://www.pbs.org/wgbh/nova/sciencenow/3210/02.html

Tha cure for some cancerz will be found in the genus Salvia. There are many scientific paperz written on their curative propertiez against many strainz of bacteria, cancerz and even AIDS.

Google "borneol + salvia". Similar to camphor in structure.

The key to killing cancer iz ta kill the cancer cellz and not tha healthy cellz. Many poisonz will kill cancerz, but they also kill the healthy cellz.

Only problem iz, there will not be much incentive to make curez from plantz that are accessible to everyone. Can't charge US$5,000 to cure a disease from a US$3.00 plant.

That's tha bitch...these plantz will cure disease - not treat them.

Fin

PS Please eidt tha link into tha shorter form so peepz will not have ta scroll back and forth.

[Green2Herman]

Colchicine can cause cancer. Hence that you use gloves and stuff then you use it to create mutants.

CB have been show great promice in the battle against cancer. Not only to treat radiation sickness and so on. But also to treat a number of cancer forms including breast- and braincancer.

[visionarybear]

colchacine may prevent mitosis in cancer cells yes, but would have to be topically used w/ no leakage as colchacine will stop mitosis in all cells, you just wont see the effect til later down the track, fast dividing are 1st to go, go say good bye to you immune system(bone marrow), liver etc if u get colchacine poisoning...(also the reason why u get sik and loose hair on chemotherapy for cancer, fast dividing cells die 1st)

the problem with developing cancer treatments is selectivity, as cancer cells are 'self' cells, there are very small and subtle differences only. truely selective drugs are hard to obtain, so the process is slow. so to fight cancer, we must 1st find how the cells are different and then find something nto kill the cell on these differences and only these differences, each cancer type is potentially a very dif drug/treatment

believe it or not, the cure is being with held due to finance, as most of the really provoking research doesnt come outa drug companies but independent/uni labs where most researches care more about the research than the money that could be made...

i stand for this personally, id rather win a nobel prize for my work than get rich off it... knowledge doesnt have a price in my mind...

[Green2Herman]

I just thought it important to point out that it is dangerous before someone desperate gave it a try on themself.

Some links about Cannabis and cancer

Cannabis May Help Combat Cancer-causing Herpes Viruses
Tampa, FL (Sept. 22, 2004) -- The compound in marijuana that produces a high, delta-9 tetrahydrocannbinol or THC, may block the spread of several forms of cancer causing herpes viruses, University of South Florida College of Medicine scientists report.
http://www.sciencedaily.com/releases/20 ... 092627.htm

Cannabis May Offer Relief from Bowel Disorders
Researchers at the University of Bath were investigating whether cannabis -- marijuana -- can help relieve some IBD symptoms. They identified a potential new target for cannabis-based drugs to treat IBD, which includes Crohn's disease and ulcerative colitis. Some IBD patients report that their symptoms are reduced after they use cannabis
http://www.healthcentral.com/newsdetail/408/527191.html

Cannabis induced cytotoxicity in leukaemic cell lines: the role of the cannabinoid receptors and the MAPK pathway
http://www.bloodjournal.org/cgi/content ... -03-1182v1

Cannabis may help combat cancer
The chemical in cannabis that produces a high may help to combat the spread of cancer, research suggests.
http://news.bbc.co.uk/1/hi/health/3655586.stm

Marihuana kan helbrede hjernesvulst
http://www.vg.no/pub/vgart.hbs?artid=239313
(Helps against brain cancer).

'Cannabis' brain tumour drug hope
An ingredient in marijuana may be useful for treating brain cancers, say Spanish researchers from Madrid.
http://news.bbc.co.uk/1/hi/health/3561686.stm

Warning. Cannabis could be dangerous!
When smoked, the effects are usually felt fairly quickly with people feeling more relaxed, happy and
generally laid back. Strong cannabis can also lead to pointless giggling, loss of inhibitions and an
enhanced appreciation of music and colours.

[Green2Herman]

Acctualy the story about CB and cancer are quite sad. They found already in the USA in the 60 that it could stop breast cancer. DEA however went around and stopped the article removing it from all the libraries. Then the spanish found the same just some year ago they did a litterature search and found reference to the article in other articles and hence learned that it exists. They didnt however found the original article until they called the authors and learned the story about this censor. Now it seems that CB could help against several cancer forms.

[Arhuline]

Oh I pray they do...

[EA-1306]

There are so many types of cancer, many involving genetic mutation in the genes regulating apoptosis.
While many forms are treatable, and preventable, some forms at the least will never be cured without some form of gene therapy.

[visionarybear]

same goes for degeneragtive diseases EA, i.e alzheimers, it may be possible to one day 'stop' the disease mid course but never reverse the effects..brains jus not that fixable... to prevent it, at risk ppl would have to be id'd nd given prophalactic treatment, or a prophalactic gene thereapy..

cannabinoids do hold some promise for all sorts of things, i cant remeber the name off the top of my head, but one synthetic cannabis analouge has shown in testing to be 520x more efficacious than morphine...

[Mahlon]

Hey all, just thought that I would chime in on the colchicine discussion.

This chemical is indeed important, and has drastically changed the course of human history/progression.

The "Autumn Crocus" (Colchicum autumnale ) has been used for millenium to treat gout (specific form of arthritis, see link at bottom).  The chemical colchicine has been extracted from many sources, but was originally found in the Autumn crocus, and is used primarily in its' production.

Colchicine itself causes polyploids to occur for one main reason; the cessation of spindle formation, via disruption of the microtubules, during cell division, causing the duplicated chromosomes not to seperate in mitosis.

Now here's the thing, I see so often Colchicine referred to as a mutagen(causing mutations), while personally I believe that it doesn't actively cause the mutations, but with double the amount of chromosomes there is going to be a larger incidence of a visible phenotype change.  In essence, since there is now double the amount of genetic material found, and being duplicated, there is a much larger chance that a mistake will be made during the copy process.  

As for the original idea of colchicine as an anti-cancer agent, the main problem would be the side effect that we find so desirable in plants.  Yes the colchicine causes cessation of cell division, BUT it does not stop the chromosomes from doubling, and that is definitely not good for those of us in the animal kingdom.  Successful (meaning living) polyploids in animals are rare indeed, and when we have tried to induce them, have found that it is fatal in almost all cases.  Also, another problem would be whether or not it would be specific to just the cancer cells or not?

Well think that's it.

Colchicine Analogues for cancer treament:  http://www.laboratorytalk.com/news/inx/inx100.html

Gout:  http://www.arthritisinsight.com/medical ... /gout.html

Colchicine treatment:  http://www.medsafe.govt.nz/profs/Datash ... inetab.htm

Great polyploid page:  http://users.rcn.com/jkimball.ma.ultran ... loidy.html

-Dan