Spirit Plants - Discussion of sacred plants and other entheogens

Plant Matters => The Forest Floor => Topic started by: Wakinyan on February 26, 2018, 09:19:54 PM

Title: Mushrooms to treat depression
Post by: Wakinyan on February 26, 2018, 09:19:54 PM
https://www.nature.com/articles/s41598-017-13282-7


"Psilocybin with psychological support is showing promise as a treatment model in psychiatry but its therapeutic mechanisms are poorly understood. Here, cerebral blood flow (CBF) and blood oxygen-level dependent (BOLD) resting-state functional connectivity (RSFC) were measured with functional magnetic resonance imaging (fMRI) before and after treatment with psilocybin (serotonin agonist) for treatment-resistant depression (TRD). Quality pre and post treatment fMRI data were collected from 16 of 19 patients. Decreased depressive symptoms were observed in all 19 patients at 1-week post-treatment and 47% met criteria for response at 5 weeks. Whole-brain analyses revealed post-treatment decreases in CBF in the temporal cortex, including the amygdala. Decreased amygdala CBF correlated with reduced depressive symptoms."
Title: Re: Mushrooms to treat depression
Post by: Wakinyan on February 27, 2018, 02:02:53 PM
The big take away from the above article seems to be that mushrooms taken every 1 to 5 weeks can help stave off depression in even treatment resistant depression.
Title: Re: Mushrooms to treat depression
Post by: judih on February 27, 2018, 11:26:45 PM
sounds like a fine plan.
(you can't control the waves, but you can learn to surf - jon kabat-zinn)
Title: Re: Mushrooms to treat depression
Post by: mono on May 09, 2026, 03:27:47 PM
i'm mental, and have never tried psilocybin medical extract, i've heard its brand new.  i saw it in the newspaper that beto o'rouke is coming out with psilocybin extract, has anyone tried this?  thanks.

Jamison