has anyone had any experience with it yet?
information on the web is a bit scattered..
my friend owns a botanical company and provided some good links.. which i'll provide as soon as i find the
e-mail in my seemingly infinite inbox.. heh.
i do know this plant can be dangerous, but my primary interest is the tetrahydropalmatine (THP) content. which appears to be even higher than that of Corydalis ambigua!
i've searched most of the communities.. but none have posted in regards. i figured this would be a good place to start ;)
much love
What THP?
tetrahydropalmatine is said to have no recreational value to it. It's used sometimes as a sleep aid. There are questions about it's effect on the health, particularly on the liver. The indications are not to use it on a long term basis. Sorry, Teo.
Quote from: "Stonehenge"tetrahydropalmatine is said to have no recreational value to it. It's used sometimes as a sleep aid. There are questions about it's effect on the health, particularly on the liver. The indications are not to use it on a long term basis. Sorry, Teo.
lol
recreational being a matter of perspective of course ;)
for me it (in the form of corydalis extract) has been my virtual fountain of youth. nothing more recreational than feeling 10 years younger! :mrgreen:
quoted from my friends site..
THP's analgesia and sedation have been shown to work at least in part by blocking postsynaptic dopamine receptors in the central nervous system. Unlike tranquilizers though it does not affect brain serotonin levels deplete monoamine stores or block GABA receptors.
It also has been shown to stimulate the secretion of ACTH (adreno-corticotrophic hormone) by the pituitary gland which controls aspects of stress. THP also has very valuable cardiovascular actions. It has been shown to decrease the stickiness of platelets thereby protecting against stroke. It has also been shown to lower blood pressure and heart rate. THP also has been shown to have a muscle relaxing effect working on smooth muscles as well as skeletal muscles. It reduced coronary resistance increased coronary bloodflow and dilated coronary blood vessels in rabbits cats and mice. The cumulative effect is to promote rhythmic efficiency. This in effect vasodilation has been shown to be very helpful with migraine.
there is some concern about liver damage. adding a liver tonic to the mix is a good idea.
and Teo, there are some reports of mild hallucinations.. so there is hope ;)
That is very interesting, TCO. As your info suggests, it is a powerful drug and not something to play with. I would say to be very cautious with it. Adding a liver tonic may not help with the toxic effects some have noticed. Use at your own risk.